Non Interventional Studies

Modern treatments for chronic pain combine different therapeutic approaches to achieve a holistic improvement of symptoms. The focus is on functionality and the well-being of the patient. Cannabinoids are already used as second- or third-line treatments for some pain syndromes. Studies show that cannabinoids can improve pain relief by 50% or more in a substantial number of patient:ing compared to placebos.

Cannabinoid drugs fall into two categories: Monosubstance of the main active ingredient, such as dronabinol, and multisubstance phytopharmaceuticals, such as cannabis extracts (NRF 22.7, NRF 22.8, NRF 22.11). Some studies suggest that cannabis extracts have clinical superiority over dronabinol.

Possible explanations for this observation include the synergistic effect of cannabinoids and the entourage effect hypothesis, which assumes pharmacological enhancement of the effects of cannabinoids by inactive terpenes. It is also possible that a combination of these two effects is effective. In addition, combining THC with other cannabinoids such as CBD may lead to a reduction in side effects.

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Are you interested in participating in the NIS?

We are continuously looking for further physicians willing to participate in our NIS. In case you have interest in participating and contributing to our research, we look forward to hear from you.

You can find more information on the mode of action and safety of our products in the section for physicians.


Recognizing the complexity of the endocannabinoid system and respecting individual differences is crucial in designing clinical trials. This approach holds the key to successful trials, ultimately advancing patient care and outcomes.


Meike Meinzer

Head of Drug Development

Biologist with focus on phytomedicine

Expert on cannabinoids and their therapeutic use

Scientific and clinical conceptualisation

Learn more about our ongoing research projects

Traditional Use of Cannabis

An in-depth investigation in the traditional use of the Cannabis plant and the and the diversity of landraised genetics

Genetic Preservation

Through our research cooperation with IBB and University Valencia, we optimise our genetics to be viroid resistant and genetically stable.


In search of premium quality mother plants, we conduct an ongoing phenohunt program through our network of authorised cultivation partners.

Personalizing Treatments

We aim to unlock precision medicine by capturing patient reported outcomes and driving point of care innovation.

Tissue Culture

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